Lotiramine
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This substance is often used by crime lords to keep their subordinates from revealing too much information if arrested or captured. By itself, lotiramine is harmless. However, when it interacts with certain interrogation drugs, such as skirtopanol, the combination induces chemical amnesia. If too much of one or the other is taken or administered, the prisoner can die of the chemical interaction, which can take the form of severe convulsions or internal hemorrhaging.